Yes Man tells the story of Danny, recently single, falling into loneliness and isolation and who was advised by a stranger on a bus to say 'yes' more. He did just that for a year and his life was totally transformed.
I suppose life is like that. If we look at things in a more positive light and accept what the universe has to offer, new opportunites will present themselves. Indeed, a little willingness can take anyone to the most wonderful of places.